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Rejuran NYC - Under-Eye Injections & Salmon DNA Microneedling in Midtown Manhattan

Two ways to regenerate. One goal: healthier-looking skin.

Rejuran uses salmon-derived polynucleotides (PDRN) to help skin repair, rehydrate and rebuild from within. At JLoo Beauty Experts, you can have it as a targeted injection or infused across the face with microneedling.

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★ 4.9 Google Rating • Board-Certified NP • MD-Supervised • Midtown NYC

Rejuran in NYC: The Short Answer

Rejuran is a Korean regenerative skin treatment made from polynucleotides (PN or PDRN), purified DNA fragments derived from salmon. It does not add volume like filler. It improves the quality of the skin itself: hydration, texture, fine lines and elasticity. JLoo Beauty Experts in Midtown Manhattan offers Rejuran I under-eye injections ($499 for first-time clients) and Rejuran Healing Essence with microneedling or as a targeted injection ($650 for first-time clients). The usual price for each is $950.

Why Choose JLoo for Rejuran in NYC?

  • Board-Certified Medical Oversight: Rejuran is performed under Medical Director Joanne Loo, MS, AGPCNP-BC, with MD oversight from Dr. Jade Hon.
  • The Right Rejuran for the Job: Rejuran I for the under-eyes, Rejuran Healing Essence for the face. We explain the difference before you book.
  • Anatomy-Led Plans: Rejuran, PRF and PRF EzGel are all available here, so you are matched to the treatment that fits your skin, not the trend.
  • 3D Skin Analysis: We assess your skin before treatment and track progress across your series.
  • Midtown Convenience: 505 8th Ave, steps from Penn Station and Hudson Yards.
Treatment room at JLoo Beauty Experts medspa in Midtown Manhattan
Board-Certified Care
4.9★ Rated in NYC
Natural, Regenerative Results

What Is Rejuran?

Rejuran is a regenerative skin treatment first popularized in Korea and now widely requested in New York. It is built around polynucleotides, purified DNA fragments derived from salmon, which support the skin's natural repair processes.

A useful way to think about it: filler adds volume. Rejuran improves the skin.

That is why it is often linked with Korean "glass skin" and nicknamed the salmon DNA facial. It does not create a dramatic change overnight. It builds improvement gradually by supporting hydration, elasticity, texture and collagen.

Microneedling with Rejuran healing essence at JLoo NYC

Three Ways to Have Rejuran at JLoo

Rejuran I (Under-Eye Injection)

Rejuran I is our go-to for clients who want to restore hydration and improve the overall quality of delicate under-eye skin. It works with the skin's own biology, using salmon-derived polynucleotides (PDRN) to support tissue repair, thicken thin skin and smooth out crepey texture from within. Think of Rejuran as deep, lasting hydration at the cellular level.

Best for: Dehydrated under-eye skin, crepey texture, fine lines, thin or fragile skin, and clients focused on long-term skin quality rather than volume.

First-time client price: $499 (usual price $950)

Compare all under-eye treatments

Microneedling with Rejuran Healing Essence (Salmon DNA Facial)

This treatment combines microneedling with Rejuran's salmon-derived PDRN to take skin rejuvenation deeper. The microneedling creates micro-channels that allow the Rejuran essence to absorb more effectively, sending regenerative signals to the skin to help it repair, rebuild and glow from within. It is a beautiful pairing for clients investing in skin longevity.

Best for: Overall skin quality, texture and collagen induction. Especially suited to dry, dull or sensitive skin, enlarged pores, early fine lines and marks left after breakouts.

First-time client price: $650 (usual price $950)

What to expect from Rejuran microneedling

Rejuran Healing Essence Injection (Face)

Rejuran Healing Essence placed with a series of very small injections into the areas that need it most, instead of across the whole face.

Best for: Targeted areas with fine lines and localized skin quality concerns.

First-time client price: $650 (usual price $950)

Rejuran Options at a Glance

Rejuran IRejuran microneedlingRejuran Healing Essence injection
Treatment areaUnder-eyesFull faceTargeted areas of the face
How it is deliveredVery small injectionsMicroneedling with the essence infusedVery small injections
Main goalHydration and thicker, smoother under-eye skinOverall skin quality, texture and glowFine lines and localized skin quality
Typical plan2 to 3 sessions, 3 to 4 weeks apartA series, 4 to 6 weeks apartSet at your consultation
DowntimeSmall bumps or bruising possible for 1 to 3 daysRedness and tightness for 24 to 48 hoursSmall bumps or bruising possible for 1 to 3 days
First-time client price$499$650$650
Usual price$950$950$950

What Rejuran Can and Can't Do

Rejuran shines when the concern is skin quality, not volume.

Rejuran Can Help Improve

  • Crepey, crinkled texture
  • Fine lines
  • Thin, fragile or dehydrated skin
  • Mild loss of elasticity
  • Dullness and a tired look related to skin quality

Rejuran Is Not Designed For

  • Significant tear trough hollowing that needs volume
  • Under-eye bags caused by fat pads
  • Dark circles that are mainly pigment

If hollowing is your main concern, PRF EzGel is usually the better starting point. That is why every plan begins with a consultation.

Rejuran vs. PRF vs. Filler

RejuranPRF (Liquid Gold PRF, PRF EzGel)HA filler
What it isSalmon-derived polynucleotides (PDRN)Platelet-rich fibrin from your own bloodHyaluronic acid gel
Main jobHydration and skin qualityCollagen stimulation and regeneration; PRF EzGel adds subtle supportAdds volume
Blood draw neededNoYesNo
Best forThin, crepey, dehydrated skinThin skin and mild to moderate hollowingSignificant volume loss
How results appearGradually, over a seriesGradually, over a seriesImmediately
Used under the eyes at JLooYesYesNo

Rejuran I has a similar texture-improving benefit to our Liquid Gold PRF. Rejuran leans more heavily into hydration, while Liquid Gold focuses on natural collagen stimulation and regeneration. For under-eye hollowness and volume restoration, PRF EzGel is the better match.

Compare all three under-eye treatments side by side

What to Expect

Step 1

Consultation

We assess your skin, talk through your goals and confirm which Rejuran option fits, or whether PRF or PRF EzGel would serve you better.

Step 2

Numbing

A medical-grade topical numbing cream is applied to the treatment area.

Step 3

Treatment

Rejuran I is placed under the eyes in very small amounts. With Rejuran microneedling, the essence is infused across the face as micro-channels are created.

Step 4

Aftercare

Skip heavy exercise and alcohol for the rest of the day, keep skincare gentle and avoid rubbing the area for 24 hours. You will leave with aftercare instructions for your plan.

Rejuran I Results Timeline

  • Days 1 to 3: Mild swelling or tiny bumps at the injection points. Bruising is possible.
  • Weeks 1 to 2: Early hydration improvement. Skin may look slightly smoother.
  • Weeks 3 to 6: Texture changes become more noticeable. Crepiness softens and fine lines look less etched.
  • After a series: Under-eye skin looks healthier and thicker, and makeup tends to sit better.

Rejuran Cost in NYC

TreatmentFirst-time client priceUsual price
Rejuran I under-eye injection$499$950
Microneedling with Rejuran Healing Essence (face)$650$950
Rejuran Healing Essence injection (face)$650$950

First-time client pricing is for clients new to JLoo Beauty Experts. The cost of your consultation goes toward your treatment. Cherry Pay financing is available.

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Smart Pairings with Rejuran

Rejuran I + PRF EzGel

Rejuran I for hydration and skin quality, PRF EzGel for under-eye hollowness and volume restoration.

Rejuran + PRF Microneedling

Pair salmon-derived PDRN with your own growth factors for a fuller regenerative plan.

Rejuran + Ultherapy PRIME

Ultherapy PRIME lifts the deeper support layer, while Rejuran improves the skin on the surface.

Rejuran in Midtown Manhattan, NYC

JLoo Beauty Experts is at 505 8th Ave, Suite 23-03, at 35th Street, steps from Penn Station and a short walk from Hudson Yards and Herald Square. Koreatown is a few blocks east. Rejuran works best as a series, and a central location makes it easier to complete yours.

FAQ

Frequently Asked Questions About Rejuran in NYC

What is Rejuran?

Rejuran is a regenerative skin treatment made from polynucleotides (PN or PDRN), purified DNA fragments derived from salmon. It supports the skin's own repair processes to improve hydration, texture, fine lines and elasticity. It does not add volume the way filler does.

Is Rejuran the same as a salmon DNA facial?

"Salmon DNA facial" and "salmon sperm facial" are popular names for treatments that use salmon-derived polynucleotides. At JLoo Beauty Experts, that treatment is microneedling with Rejuran Healing Essence, which infuses the essence across the face through tiny micro-channels.

What is the difference between Rejuran I and Rejuran Healing Essence?

Rejuran I is formulated for delicate areas and is used for under-eye injections that target crepey, thin, dehydrated skin. Rejuran Healing Essence is used across the face with microneedling for overall skin quality, texture and glow, or as a targeted injection for localized concerns.

Is Rejuran a filler?

No. Filler adds volume. Rejuran improves the skin itself. If your main concern is an under-eye hollow, PRF EzGel is usually the better match, and the two can be combined.

Does Rejuran help dark circles?

It can improve the look of dark circles when the darkness is related to thin skin and poor skin quality. If dark circles are mainly pigment or the shadow of a hollow, other treatments may be more effective.

How many Rejuran sessions will I need?

For Rejuran I under-eye injections, most clients benefit from 2 to 3 sessions spaced 3 to 4 weeks apart, followed by maintenance based on their goals. Microneedling with Rejuran Healing Essence is also done as a series, usually spaced 4 to 6 weeks apart. Your provider confirms the number at your consultation.

Does Rejuran hurt?

A medical-grade numbing cream is applied before every Rejuran treatment. Most clients describe injections as brief pinches and microneedling as mild pressure or warmth.

Is there downtime after Rejuran?

Downtime is low. After Rejuran I, small bumps or mild swelling at the injection points usually settle within 24 to 72 hours, and bruising is possible. After Rejuran microneedling, expect redness and tightness for 24 to 48 hours.

Should I choose Rejuran or PRF?

Both improve skin quality. Rejuran leans more heavily into hydration, while Liquid Gold PRF focuses on natural collagen stimulation and regeneration using your own blood. For hollowing, PRF EzGel adds support that Rejuran does not. Many clients have a plan that includes more than one.

Who should not have Rejuran?

Rejuran is derived from salmon DNA, so tell us if you have a fish or seafood allergy. We also do not treat during pregnancy or breastfeeding, or over an active skin infection. Your provider reviews your medical history at your consultation.

How much does Rejuran cost in NYC?

At JLoo Beauty Experts, Rejuran I under-eye injections are $499 for first-time clients. Rejuran Healing Essence, either with microneedling or as an injection, is $650 for first-time clients. The usual price for each is $950 per session.

Where can I get Rejuran in Midtown Manhattan?

JLoo Beauty Experts is at 505 8th Ave, Suite 23-03, New York, NY 10018, steps from Penn Station and a short walk from Hudson Yards and Herald Square.

JLoo Beauty Experts

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